Academic Catalog


Course Code: 2190433
METU Credit (Theoretical-Laboratory hours/week): 3(2-2)
ECTS Credit: 9.0
Department: Molecular Biology And Genetics
Language of Instruction: English
Level of Study: Undergraduate
Course Coordinator: Assoc.Prof.Dr. ADA DEVRM SON
Offered Semester: Fall Semesters.
Prerequisite: Set 1: 2380307 , 2380308
Set 2: 2380420
Set 3: 2380353
Set 4: 2340413
One of the sets above should be completed before taking GENE433 MOLECULAR MODELING AND PROTEIN STRUCTURE PREDICTION .

Course Content

Current developments in biology, nanotechnology, biotechnology and large scale DNA sequencing increased the role of protein structure prediction more important than ever. The objective of this course is to provide a background for the molecular biologist by outlining the principle concepts and limitations in 3D protein modeling. The available algorithms, programs and data banks used in modeling and protein structure prediction will be reviewed. More importantly methods to evaluate the performance of these algorithms and programs will be discussed as a new approach in modeling and structure prediction emerges almost every day.