Academic Catalog

BIN504 PROBABILISTIC AND STATISTICAL MODELING FOR BIOINFORMATICS

Course Code: 9080504
METU Credit (Theoretical-Laboratory hours/week): 3(3-0)
ECTS Credit: 8.0
Department: Bioinformatics
Language of Instruction: English
Level of Study: Graduate
Course Coordinator: Assist.Prof.Dr AYBAR CAN ACAR
Offered Semester: Fall or Spring Semesters.

Course Content

This course will introduce statistical modeling and inference techniques applied to biological problems. The course will cover standard statistical methods, such as multiple regression and principle component analysis, and more recent statistical techniques, such as maximum likelihood methods. Among the techniques covered will be Monte-Carlo-Markov chains using the Metropolis-Hastings algorithm and Gibbs sampling. In addition, the course will cover the use of statistical techniques such as Hidden Markov Models to model family of sequence and structures. Kernel methods and Support Vector Machines for computational biology will also be covered.